Selective decontamination of the digestive tract.
نویسندگان
چکیده
منابع مشابه
Selective decontamination of the digestive tract.
Ventilator-associated pneumonia usually originates from the patient's oropharyngeal microflora. In selective digestive decontamination, topical antibiotics are applied to the oropharynx and stomach for prevention of pneumonia and other infections, possibly reducing infection-related mortality. Selective digestive decontamination is also used for the prevention of gut-derived infections in acute...
متن کاملSelective decontamination of the digestive tract: all questions answered?
Although many studies have shown beneficial effects of SDD on the incidence of respiratory tract infections, SDD did not become routine practice because mortality reduction was not demonstrated in individual trials, beneficial effects on duration of ventilation, ICU stay or hospital stay were not demonstrated, cost-efficacy had not been demonstrated, and selection of antibiotic resistance was c...
متن کاملIs selective decontamination of the digestive tract safe?
TO THE EDITOR—The recent systematic review of 157 studies of pneumonia prevention methods in the intensive care unit (ICU) by Roquilly et al is of great interest [1]. Two of their findings—the importance of systemic antimicrobial therapy in selective decontamination of the digestive tract (SDD) and the apparent benefit among 29 randomized studies of SDD with 6089 patients vs its insignificance ...
متن کاملSelective Decontamination of the Digestive Tract Reduces Pneumonia and Mortality
Selective decontamination of the digestive tract (SDD) has been subject of numerous randomized controlled trials in critically ill patients. Almost all clinical trials showed SDD to prevent pneumonia. Nevertheless, SDD has remained a controversial strategy. One reason for why clinicians remained reluctant to implement SDD into daily practice could be that mortality was reduced in only 2 trials....
متن کاملSelective digestive decontamination is superior to selective oropharyngeal decontamination
are interested in the debate on the effi cacy and safety of selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) raised by Schultz and Haas in their review [1]. Th e authors concluded that 'SDD and SOD are equally eff ective with respect to the prevention of mortality' [1]. Th is statement is based on the results of a Dutch randomized controlled trial [2],...
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ژورنال
عنوان ژورنال: BMJ
سال: 1989
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.299.6713.1413